Carotid Cavernous Fistulas (CCF). What an ophthalmologist should know: Review of cases undergoing endovascular treatment at the Dr. Asenjo Neurosurgery Institute, Santiago, Chile

Authors

  • Mario Daniel Echeverría Martínez Instituto de Neurocirugía Asenjo
  • Marcos Ruiz Instituto de Neurocirugía Asenjo
  • Tomás Becker Pontificia Universidad Católica de Chile
  • Alejandro Venegas Instituto de Neurocirugía Asenjo
  • Bárbara Pascual Pontificia Universidad Católica de Chile

DOI:

https://doi.org/10.56172/oftalmica.v22i.34

Keywords:

CCF, carotid cavernous fistula, red eye, endovascular therapy, neuroradiology, interventional neuroradiology, embolization, NRx

Abstract

Introduction: Carotid cavernous fistula are abnormal communications between arterial cerebral system and cavernous sinus. First line treatment nowadays is endovascular. The objetive of this study is to report a series of cases that received endovascular treatment at Instituto de Neurocirugía Dr. Asenjo at Chile hospital. Materials and Methods: Review of clinical records review of patients treated with an endovascular approach between 2017 and 2022. Clinical data reviewed included patient demographics and imaging findings. Results: We registered 28 patients, average age for the group was 54.8 years, 82.1% female. Most commonly reported symptoms were chemosis, proptosis, oculomotility alterations, headache or ocular pain. 11 cases were cases of a direct AV fistula. 16 cases were indirect and 1 case was mix case. Discussion: Carotid Cavernous fistulas must be suspected this pathology in a patient with or without cranial trauma, that progresses to proptosis, chemosis, with or without oculomotor or visual alterations. Clinical characterization of our patients was concordant with the reported in literature considering symptomatology, however, with predominance of an indirect and spontaneous fistulas. Conclusions: Ophthalmological evaluations is fundamental to determine differential diagnosis and management of concomitant pathology. Referral to interventional neuroradiology department is key for the patient to get the best treatment for it, endovascular treatment of the CC fistulas.

Downloads

Download data is not yet available.

References

Liu P, Liu Y, Shi Y, An Q, Zhu W, Liu Y, et al. The vascular architecture of cavernous sinus dural arteriovenous fistula and its impact on endovascular treatment approach selection and outcome. World Neurosurg. 2022 Oct;166:e770-80. https://doi.org/10.1016/j.wneu.2022.07.094 DOI: https://doi.org/10.1016/j.wneu.2022.07.094

Diagnosis and Management of Carotid Cavernous Fistulas - American Academy of Ophthalmology [Internet]. [cited 2022 Nov 23]. Available from: https://www.aao.org/eyenet/article/diagnosis-management-of-carotid-cavernous-fistulas

Hoffman H, Ashok Kumar A, Wood JS, Mikhailova T, Yoo JH, Wakeman MB, et al. Outcomes after endovascular treatment of direct carotid cavernous fistulas: Systematic review and meta-analysis. World Neurosurg. 2022 Nov 2; https://doi.org/10.1016/j.wneu.2022.10.123 DOI: https://doi.org/10.1016/j.wneu.2022.10.123

Marinkovic S, Gibo H, Vucevic R, Petrovic P. Anatomy of the cavernous sinus region. J Clin Neurosci. 2001 May;8 Suppl 1:78-81. https://doi.org/10.1054/jocn.2001.0883 DOI: https://doi.org/10.1054/jocn.2001.0883

Ringer AJ, Salud L, Tomsick TA. Carotid cavernous fistulas: anatomy, classification, and treatment. Neurosurg Clin N Am. 2005 Apr;16(2):279-95, viii. https://doi.org/10.1016/j.nec.2004.08.004 DOI: https://doi.org/10.1016/j.nec.2004.08.004

Ellis JA, Goldstein H, Connolly ES, Meyers PM. Carotid-cavernous fistulas. Neurosurg Focus. 2012 May;32(5):E9. https://doi.org/10.3171/2012.2.FOCUS1223 DOI: https://doi.org/10.3171/2012.2.FOCUS1223

Feiner L, Bennett J, Volpe NJ. Cavernous sinus fistulas: carotid cavernous fistulas and dural arteriovenous malformations. Curr Neurol Neurosci Rep. 2003 Sep;3(5):415-20. https://doi.org/10.1007/s11910-003-0025-x DOI: https://doi.org/10.1007/s11910-003-0025-x

Henderson AD, Miller NR. Carotid-cavernous fistula: current concepts in aetiology, investigation, and management. Eye 2018;32:164-72. https://doi.org/10.1038/eye.2017.240 DOI: https://doi.org/10.1038/eye.2017.240

Bhatti MT. Orbital syndromes. Semin Neurol. 2007 Jul;27(3):269-87. https://doi.org/10.1055/s-2007-979685 DOI: https://doi.org/10.1055/s-2007-979685

Jozef Č. Carotid-cavernous fistula from the perspective of an ophthalmologist A Review. Cesk Slov Oftalmol 2020;1:1-8. https://doi.org/10.31348/2020/8 DOI: https://doi.org/10.31348/2020/8

Sarkis Y, Worden A, Schreiber T, Lapitz A. High index of suspicion: diagnosing a carotid-cavernous fistula. BMJ Case Rep 2023;16. https://doi.org/10.1136/bcr-2022-253473 DOI: https://doi.org/10.1136/bcr-2022-253473

Williams ZR. Carotid-Cavernous Fistulae: A Review of Clinical Presentation, Therapeutic Options, and Visual Prognosis. Int Ophthalmol Clin 2018;58:271-94. https://doi.org/10.1097/IIO.0000000000000215 DOI: https://doi.org/10.1097/IIO.0000000000000215

Published

2022-06-30

How to Cite

Echeverría Martínez, M. D., Ruiz, M., Becker, T., Venegas, A., & Pascual, B. (2022). Carotid Cavernous Fistulas (CCF). What an ophthalmologist should know: Review of cases undergoing endovascular treatment at the Dr. Asenjo Neurosurgery Institute, Santiago, Chile. Revista Oftálmica, 22, 10–20. https://doi.org/10.56172/oftalmica.v22i.34

Issue

Section

Revisión de literatura